alienate是一个动词，意思是使疏远、使不友好、使隔离。英文发音为[ˈeɪliəneɪt]。

用法方面，alienate可以作为及物动词，也可以作为不及物动词。作为及物动词时，通常接受事物或人作宾语；作为不及物动词时，通常接受介词from，并且后面跟隔离的对象。

例句1：His constant criticism of her work alienated her from the rest of the team.

他对她工作的不断批评使她与团队其他成员疏远。

例句2：The strict rules and regulations in the school have alienated many students.

学校严格的规章制度使许多学生感到被隔离。

例句3：The new policy has alienated a large portion of the company's employees.

新使公司大部分员工感到被疏远。

例句4：He felt alienated from his own family because of their different values and beliefs.

因为价值观和信仰的差异，他感到与自己的家人疏远。

例句5：The government's actions have alienated its citizens and caused widespread discontent.

的行为使公民感到被隔离，并引发了广泛的不满情绪。

同义词及用法方面，alienate还可以被替换为estrange、distance、isolate等词语。：

- I don't want to estrange my friends by being too critical.

我不想通过过度批评来疏远我的朋友。

- The long distance between them has caused them to grow apart.

他们之间的长距离使他们渐行渐远。

- The new policy has isolated the company from its customers.

新使公司与客户隔离开来。

总的来说，alienate是一个贬义词，通常用于描述人与人之间的疏远、隔离，或者指某种行为导致关系变得不友好。编辑建议，在使用时要注意语境，避免给人带来负面印象。